Multifunctional GO-based hydrogel coating on Ti-6Al-4 V Alloy with enhanced bioactivity, anticorrosion and tribological properties against cortical bone

Abstract

Ti-6Al-4 V alloy, as the popular bone implants, has restrictive applications due to its poor antiwear properties, osteoinductivity, and corrosion resistance. In this work, a multifunctional PVA/PAA/GO/PDA hydrogel coating was successfully constructed on the surface of Ti-6Al-4 V by combing chemical assembly and freezing-thawing method. The biotribological properties of hydrogel coating were evaluated through constructing the Ti-6Al-4 V vs cortical bone system in simulated body fluids (SBF) lubrications. The experimental results indicate that the GO-based hydrogel coating exhibits multifunctional features, especially PVA/PAA/0.5GO/PDA, with excellent biotribological performances (82.0% wear rate reduction of the bone tissue), corrosion resistance and bioinductive activity. This work not only develops a multifunctional GO-based hydrogel but also provides a potential method for surface modification of titanium alloy bone implants.