Abstract
In this work, self-assembled core/shell nanostructures of CdS/CoFe2O4 (CFO) have been synthesized using a chemical solution method to include magnetic and fluorescent properties in a single composite material for bioapplications. Successful synthesis of the core/shell nanostructure has been evidenced from the transmission electron microscopy and x-ray diffraction results. Alternating gradient magnetometer and photoluminescence spectroscopy results confirm good magnetic and luminescent characteristics of the core/shell nanostructure. The in vitro biocompatibility of the CFO and CdS/CFO nanostructures has been studied in the Alamar blue assay in four different cell lines (MIAPaCa-2, MCF-7, KUSA-A1, and L929 cells) at different concentrations of nanostructures. The CdS/CFO nanostructure shows improved biocompatibility in all the cell lines as compared to bare CFO nanostructures at all concentrations. However, the biocompatibility for both the nanostructures is found to decrease in the KUSA-A1 cell line at higher concentrations of the nanostructures, which is due to the higher sensitivity of the KUSA-A1 cell line to the nanostructures at higher concentrations than other cell lines. Biocompatibility studies show the potentiality of these core/shell nanostructures for bio-applications.
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