Abstract

Herbal medicines are currently employed for the treatment of several types of diseases, and also employed for the improvement of Quality of Life (QOL) of patients over the world, in particular, in Asian countries. In Japan, a Japanese herbal medicine namely kampo medicine has been prescribed for the improvement of QOL of patients. Ninjinyoeito (NYT), composed of 12 herbal plants, is one of kampo medicines and used for helping recovery of diseases and improving several symptoms that suffer patients such as anemia, anorexia and fatigue. Recent scientific research approaches to kampo medicines with cells and animal models enable to prove that NYT has multiple functions for improvement of symptoms. Also, clinical studies using NYT support such actions to be widely used for the improvement of symptoms that reduce the QOL of patients.

Highlights

  • Ninjinyoeito (NYT) is a Japanese herbal medicine prescribed and clinically admired in Japan

  • NYT is composed of 12 crude ingredients, including Rehmannia root, Japanese angelica root, Atractylodes rhizome, Poria sclerotium, Ginseng, Cinnamon bark, Polygala root, Peony root, Citrus unshiu peel, Astragalus root, Glycyrrhiza, and Schisandra fruit

  • Recent scientific approaches to analyze the mechanism of action of kampo medicine including NYT enable to understand how kampo medicines act on patients and their functional sites of action [10,11,12]

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Summary

Frontiers in Nutrition

Herbal medicines are currently employed for the treatment of several types of diseases, and employed for the improvement of Quality of Life (QOL) of patients over the world, in particular, in Asian countries. In Japan, a Japanese herbal medicine namely kampo medicine has been prescribed for the improvement of QOL of patients. Ninjinyoeito (NYT), composed of 12 herbal plants, is one of kampo medicines and used for helping recovery of diseases and improving several symptoms that suffer patients such as anemia, anorexia and fatigue. Recent scientific research approaches to kampo medicines with cells and animal models enable to prove that NYT has multiple functions for improvement of symptoms. Clinical studies using NYT support such actions to be widely used for the improvement of symptoms that reduce the QOL of patients

INTRODUCTION
Contribution of NYT to Improve Neurodisorder
Myelopoiesis and Erythropoiesis
Modulation of Immunoresponses
Neuropathic Pain
Scavenging Action of NYT on Several Types of Free Radicals
Frailty in Locomotor Disease
Rehmannia Root
Japanese Angelica Root
Physiological functions
CLINICAL STUDIES USING NYT
CONCLUSION
AUTHOR CONTRIBUTIONS
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