Abstract

Primary non-Hodgkin lymphoma (NHL) of the skull is extremely rare. The authors report a case in a 19-year-old boy who presented with a progressively increasing scalp mass on background of generalized headache of 6-months duration. Imaging showed multifocal skull vault lesion with intra- and extra-cranial soft tissue masses, causing permeative destruction of underlying skull bone. Further investigation failed to identify any other evidence of systemic lymphoma. Histopathology examination of superficial scalp mass showed low grade non-Hodgkin B cell lymphoma. The precise anatomical location and multifocal nature of the neoplasm occurring in young nonimmunocompromised individual makes this case clinically and radiologically unique.

Highlights

  • Patient underwent computed superficial scalp mass was biopsiedA 19-year-old boy presented with tomography (CT) scan of the brain and diagnosis of low grade nongeneralized headache and progres- which confirmed the presence of the Hodgkin’s B-cell lymphoma was sively increasing swellings on the extra-cranial mass and showed its made (Fig. 3A)

  • Primary non-Hodgkin lymphoma (NHL) of the skull is extremely rare

  • A 19-year-old boy presented with tomography (CT) scan of the brain and diagnosis of low grade nongeneralized headache and progres- which confirmed the presence of the Hodgkin’s B-cell lymphoma was sively increasing swellings on the extra-cranial mass and showed its made (Fig. 3A)

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Summary

Patient underwent computed superficial scalp mass was biopsied

A 19-year-old boy presented with tomography (CT) scan of the brain and diagnosis of low grade nongeneralized headache and progres- which confirmed the presence of the Hodgkin’s B-cell lymphoma was sively increasing swellings on the extra-cranial mass and showed its made (Fig. 3A). Further work-up with left side of scalp which had been intra-cranial extradural extension in CT examination of neck, thorax, developing over a period of 6- left fronto-parietal (rolandic) region. Abdomen and pelvis did not reveal months His medical history was The extradural lesion exerted mass presence of lymphoma at any other otherwise unremarkable. Post contrast CT image shows mass lesion in right occipito-cerebellar region. Superficial scalp swelling in left fronto-parietal region responded well and CT revealed resolution of intracranial lesion (Fig. 3B). Patient remains symptom free in 2-year follow up period

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