Abstract

Multicentric gliomas are uncommon lesions but a fascinating clinical and scientific issue. Current opinion ranges from rejection of surgical treatment to its recommendation. We report a case of young adult who presented with one episode of generalized tonic clonic seizures and mild weakness of right hand. Imaging findings were suggestive multiple lesions in the left temporo-parietal area. Surgical decompression was performed for the larger lesion and histopathology was suggestive of glioblastoma multiforme. Based on these findings a diagnosis of multifocal glioblasotma was made. Patient was submitted for radiotherapy. In patients with multiple lesions tissue analysis is critical for treatment planning and to determine the prognosis.

Highlights

  • Multiple intracranial lesions represent a diagnostic dilemma and commonly represent metastases, lympho¬ma, infections and vascular or demyelinating disease

  • Present case is an example of multifocal glioblastoma multi¬forme (GBM) present at the same time

  • Tumor dissemination via CSF pathways has been proposed as another reason for multicentric gliomas [1]

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Summary

Multifokal Glioblastoma Multiforme ÖZET

Bu konuda görüşler cerrahi tedaviden tavsiyelere kafdar değişebilir. Biz sağ elinde hafif zayıflık olan ve yaygın tonik klonik nöbetleri olan genç bir hastayı sunduk. Görüntüleme bulguları sol temporo-pariyatal bölgede multipl lezyonları gösteriyordu.cerrahi olarak dekopmresyon tercih edildi. Çıkarılan büyük parçanın patoloji sonucu glioblastoma multiforme geldi.Tüm bulgular incelendiğinde multifokal glioblastoma tanısı konuldu. Multifokal lezyonları olan hastalarda tedavi planlama yapmak için doku analizi gereklidir. Anahtar kelimeler: Glioblastoma, multisentrik glioma, multifokal glioma, multipl serabral lezyonlar

INTRODUCTION
Multifocal glioblastoma multiforme
DISCUSSION
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