Abstract
Epithelioid hemangioendotheliomas are rare neoplasms involving any sites including soft tissue, lung, liver, kidney, etc. and many more. A multifocal hemangioendothelioma is extremely rare, and it can very well be mistaken as angiosarcoma with metastasis. Here, we describe a case of multifocal hemangioendothelioma which radiologically appeared like multiple metastatic lesions in paraspinal muscle, liver, kidney, adrenal, lung and gluteus muscle arising from renal cell carcinoma, lung carcinoma, or renal angiosarcoma. But histologically the picture is characteristic of epithelioid hemangioendothelioma. Morphological differentiation between an epithelioid hemangioendothelioma and epithelioid angiosarcoma is more helpful than the immunohistochemical markers.
Highlights
Epithelioid hemangioendothelioma is an uncommon endothelial cell malignancy of low-grade malignant potential
The histomorphology is characteristic with unique recurrent genetic abnormalities which helps the pathologist in avoiding any potential diagnostic pitfalls
CASE PRESENTATION We would like to report a case of multifocal epithelioid hemangioendothelioma
Summary
Epithelioid hemangioendothelioma is an uncommon endothelial cell malignancy of low-grade malignant potential. It can occur in various sites like lung, soft tissue, kidney, liver, other viscera and bone, multifocal lesions are extremely rare. A 52-year-old man with type 2 diabetes mellitus and chronic kidney disease on hemodialysis, had multiple lesions in liver, lung, right kidney, right adrenal, inferior surface of duodenum, left paraspinal muscle, right gluteus maximus and right chest wall.
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