Multifocal Electroretinogram and Fundus Autofluorescence Findings in Acute Zonal Occult Outer Retinopathy during a Three- Year Follow-Up

Abstract

Acute zonal occult outer retinopathy is a disease difficult to diagnose. Within this pathology, many clinical and para-clinical tests appear normal regardless the great advances in technology. However, the findings we discovered with electrophysiology when paired with a thorough clinical anamnesis are the more reliable parameters for giving the right diagnosis.We present a clinical case of a 26 year old patient with diagnosis of acute zonal occult outer retinopathy whose optical coherence tomography and fluorescein angiography results were normal while the results of the wide field electroretinogram and multifocal electroretinogram showed alterations in the outermost layers of the retina which correlated with inferior arcuate defect in the visual field and peri-macular areas of hyperautofluorescence in the auotofluorescence. The evolution of the case is shown during 3 years appreciating the disappearance of the autofluorescence as well as progressive improvement in the visual field.