Multi-factor analysis of factors influencing the outcomes in patients with benign prostatic hyperplasia and overactive bladder after transurethral resection of the prostate

Abstract

Objective To study the factors influencing the factors influencing the prognosis in patients with benign prostatic hyperplasia(BPH)and overactive bladder(OAB)subject to the transurethral resection of the prostate(TURP). Methods A total of 216 patients diagnosed with BPH and OAB in our hospital were treated with TURP.Clinical data including age, blood pressure, blood glucose, prostate volume, residual urine volume, average urinary flow rate, maximum urinary flow rate, detrusor instability, international prostate symptom score(I-PSS), urinary infection, urinary retention and other aspects were collected in our study.The related data were used for univariate analysis first.Multivariate analysis was done by the Logistic regression. Results Univariate analysis showed that the following features were associated with the prognosis of patients with TURP: residual urine volume(χ2= 4. 761,P< 0. 05), I-PSS(χ2= 9. 313,P< 0. 05), maximum urinary flow rate(χ2= 4. 539,P< 0. 05) and detrusor instability(χ2= 5. 252,P< 0. 05). Multivariate analysis showed that the following features were independently associated with prognosis of patients subject to TURP:I-PSS and detrusor instability. Conclusion I-PSS[odds ratio(OR)= 1. 952,P< 0. 05] and detrusor instability(OR= 2. 791,P< 0. 05)could be independent predictive factors in the clinical efficacy of TURP in the patients with BPH and OAB. Key words: Benign prostatic hyperplasia; Overactive bladder; International prostate symptom score; Risk factors