Abstract

Multidrug-Resistant<i>Salmonella enterica</i>, Democratic Republic of the Congo

Highlights

  • Disk diffusion (EUCAST standardised disk diffusion method) Medium: Mueller-Hinton agar Inoculum: McFarland 0.5 Incubation: Air, 35±1oC, 18±2h Reading: Read zone edges as the point showing no growth viewed from the back of the plate against a black background illuminated with reflected light

  • Breakpoints relate to high dose therapy (2 g x 3)

  • Disk diffusion (EUCAST standardised disk diffusion method) Medium: Mueller-Hinton agar + 5% defibrinated horse blood and 20 mg/L β-NAD (MH-F) Inoculum: McFarland 0.5 Incubation: 5% CO2, 35±1oC, 18±2h Reading: Read zone edges as the point showing no growth viewed from the front of the plate with the lid removed and with reflected light

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Summary

Breakpoint tables for interpretation of MICs and zone diameters

Streptococcus groups A, B, C and G Streptococcus pneumoniae Viridans group streptococci Haemophilus influenzae Moraxella catarrhalis Neisseria gonorrhoeae Neisseria meningitidis Gram-positive anaerobes Clostridium difficile Gram-negative anaerobes Helicobacter pylori Listeria monocytogenes Non-species related breakpoints

Moraxella catarrhalis
Benzylpenicillin Ampicillin
Letters for comments on disk diffusion
Amikacin Gentamicin Netilmicin Tobramycin
Miscellaneous agents
Doripenem Ertapenem Imipenem Meropenem
Doxycycline Minocycline Tetracycline Tigecycline
Antibiotic agent
NoteA NoteA NoteA
NoteA NoteA NoteA NoteA
NoteA NoteA
Chloramphenicol Colistin Daptomycin
Oxacillin Cloxacillin Dicloxacillin Flucloxacillin
Netilmicin Streptomycin
NoteA NoteB
Telavancin Vancomycin
Streptococcus pneumoniae
Cefaclor Cefadroxil Cefalexin Cefazolin Cefepime
NA NoteA
Viridans group streptococci
NoteB NoteB NoteB NoteB
Ertapenem Imipenem Meropenem
Haemophilus influenzae
NoteD NoteB
Norfloxacin Ofloxacin
Neisseria gonorrhoeae
Cefaclor Cefadroxil Cefalexin Cefazolin Cefepime Cefixime Cefotaxime
Clostridium difficile
Listeria monocytogenes
MIC breakpoint Disk Zone diameter Notes
Ciprofloxacin Levofloxacin Moxifloxacin Nalidixic acid Norfloxacin Ofloxacin
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