Abstract
Multidrug-resistant Gram-negative bacilli producing oxacillinases and Metallo-β-lactamases isolated from patients in intensive care unit - Annaba hospital - Algeria (2014-2016)
Highlights
Infections in intensive care units (ICUs) are becoming recurrent and increasingly complicated
The aim of the present study is to investigate the prevalence of Gram-negative bacilli multidrug-resistant (MDR-Gram negative-bacilli (GNB)) and characterization of genes encoding for carbapenemases isolated from the intensive care unit of Ibn Rochd hospital, Annaba, Algeria, over a period of 18 months
The prospective study on multi-drug resistant bacteria (MDR)-GNB, isolated from various specimens was performed over 18 months (December 2014 to May 2016) from distal protected sampling (DPS), pus, rectal swab (RS) and urine taken from patients hospitalized in the intensive care unit (Ibn Rochd hospital, Annaba)
Summary
Infections in intensive care units (ICUs) are becoming recurrent and increasingly complicated. They cause high morbidity and mortality over the world. These infections are usually caused by multi-drug resistant bacteria (MDR), especially Gram negative-bacilli (GNB), where their prevalence in Algeria and all over the world increases in a worrying way and represents a serious public health problem (Baba Ahmed and Arlet, 2014). Pseudomonas aeruginosa and Acinetobacter baumannii appears as the major agent causing infections in intensive care units, especially for immunocompromised patients. Their ability to develop resistance to antimicrobial agents makes treatment of these infections ever more difficult (McGowan, 2006). The infections caused by these MDR bacteria are essentially related to the frequent use of invasive procedures
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