Abstract

Gastric endocrine cell carcinoma is rare. The multidisciplinary treatment of a 52-year-old man with endocrine cell carcinoma and liver metastasis was reported. A total gastrectomy and left hepatectomy were performed. After the operation he had adjuvant plus maintenance chemotherapy of UFT, 5-FU, ADM, and MMC. MMC, 5-FU, ADM, and CDDP had high chemosensitivity and were used for intra-arterial infusion chemotherapy. Furthermore they were periodically injected into the hepatic artery from a vascular access device. Nine months later he died of liver metastases in spite of aggressive treatments. Endocrine cell carcinoma with liver metastasis is one of the most serious diseases and we need a more advanced treatment.

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