Multidisciplinary team diagnosis and therapy for a myeloid sarcoma/AML patient with adrenal mass after allogeneic hematological stem cell transplantation

Abstract

Myeloid sarcoma is a rare hematological neoplasm that may develop de novo or concurrently with acute myeloid leukemia (AML), or represent the initial manifestation of relapse in a previously treated AML in remission. A 44-year-old man was diagnosed with testis MS in his local hospital. A month later, November 2010, our department confirmed the clinical diagnosis of AML through his bone marrow biopsy and aspirate. The patient underwent allogeneic hematological stem cell transplantation from his sister and achieved complete remission. Five months later, however, a mass in his adrenal was revealed by Positron Emission Tomography-Computer Tomography (PET-CT). After a multidisciplinary team diagnosis, radiotherapy for this lesion was performed. As of the follow up conducted until March 2013, the patient remains healthy and shows no evidence of recurrent MS or leukemia.