Abstract
Materials and methods EPIMAN-II Thousand is a national multi-site collaborative study dedicated to the clinical sub-types of mania. It involved training 317 French psychiatrists working in different sites representative of all France. The study actually succeeded in recruiting 1090 cases admitted for acute mania (DSM-IV criteria). Manic symptomatology was assessed using the Mania Rating Scale (MRS; 10 items). A checklist of depressive symptoms, CLDS (McElroy et al. modified, 10 items) and MADRS (10 items) were used to assess co-existing depression. Principal component analysis (PCA) was conducted after rotation on combined items from MRS + MADRS (20 items). Affective Temperaments (AT) were assessed by using the full TEPMS-A French version (84 items, Hantouche et al., 2001). Correlation analyses were conducted between mean factorial scores and mean scores of the TEMPS-A.
Highlights
Open AccessHagop Akiskal*1, Elie-Georges Hantouche[2], Jean-Michel Azorin[3], Sylvie Lancrenon[4], Liliane Chatenet-Duchene[5] and Charles Gury[5]
Previous data deriving from EPIMAN (104 patients) study had suggested a rich multidimensional phenomenology of mania beyond the conventional dichotomy of euphoric versus dysphoric forms (Akiskal et al, 2003)
"EPIMAN-II Thousand" is a national multi-site collaborative study dedicated to the clinical sub-types of mania
Summary
Hagop Akiskal*1, Elie-Georges Hantouche[2], Jean-Michel Azorin[3], Sylvie Lancrenon[4], Liliane Chatenet-Duchene[5] and Charles Gury[5]. Address: 1International Mood Center, UCSD, San Diego, USA, 2Mood Center, Université Paris Vi, Pitié-Salpetriere Hospital, Paris, France, 3Sainte Marguerite Hospital, Marseille, France, 4Sylia-Stat, Antony, France and 5CNS Department Sanofi-Aventis, Paris, France. Published: 28 February 2006 Annals of General Psychiatry 2006, 5(Suppl 1):S140 doi:10.1186/1744-859X-5-S1-S140. cecocIonnteternat/tfiolensa/lpdSof/c1i7e4ty4-o8n59BXra-5in-Sa1n-dfuBlle.phdafv">iohuerr:e2In.onn Brain and Behaviour Meeting abstracts – A single PDF containing all abstracts in this Supplement is available
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