Abstract
Multdimensional gas chromatography analysis of air paticles for the tobacco alkaloid continine is described. The analytical procedure requires little sample preparation. Unambiguous indentification of continue and nicotine in cigarette smoke and indoor air samples was achieved by precise, reproducible retention times observed with two parallel analytical columns of different polarities and a nitrogen-specific detector. Further investigation of smoking and environmental variables is needed to validate the use of continine as a marker compound for environmental tobacco smoke particulate matter.
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