Multidetector-row computed tomography for noninvasive coronary imaging

Abstract

Computed tomography (CT) permits cross-sectional imaging of the heart. Temporal and spatial resolutions of the technique have been insufficient to cover the heart without motion artefacts until the recent advent of multidetector systems with more than 16 detector rows. The modality is now suited for noninvasive imaging of the coronary arteries, producing detailed morphologic images of the entire coronary tree with upto 0.4 mm of spatial resolution, within a single short breath-hold duration. CT imaging goes beyond the delineation of the coronary lumen as provided by selective invasive angiography; the plaque burden of the coronary artery wall can be visualized directly, utilizing soft-tissue contrast and a high sensitivity even for the small calcifications that are present in hard plaque formations. Therefore, CT combines elements of catheterization angiography for lumen imaging and of intravascular ultrasound imaging for coronary wall imaging. However current CT technology is not yet able to compete with the temporal or spatial resolution of catheterization angiography nor does it provide the detailed spatial or contrast resolution of intravascular ultrasound imaging. At present, its use is therefore restricted to complementing the invasive modalities in appropriate indications. Although CT entails significantly less risk than the invasive procedures, the risks of radiation dose exposure and contrast agent application are not negligible. In the foreseeable future, if the current rate of technological advancement continues, CT may replace the invasive modalities in routine care for diagnostic purposes.