Multicentric Gorham's Disease in the Oral and Maxillofacial Region: Report of a Case and Review of the Literature

Abstract

Gorham's disease, also known as massive osteolysis, Gorham-Stout syndrome, vanishing bone disease, and phantom bone disease, is a rare disease characterized by progressive osteolysis and proliferation of fibrous connective tissue similar to that of vascular malformations.1 It was first described by Jackson in 18382 and characterized pathologically by Gorham and Stout in 1955.3 It is more common in young adults with no significant gender difference and affects mainly the pelvis, humerus, and axial skeleton.