Multi-variate stepwise discriminant analysis research affecting portal hypertension's grade factors of liver function.

Abstract

The ideal time for selecting portal hypertension operation is the accurate judgement of the grade of liver function, yet the present criterion in grading liver function is controversial. 50 patients with 20 factors related to portal hypertension were undergone stepwise discriminant analysis by using SAS software on the IBM/PC computer (significance level alpha = 0.05). The results show that ascites degree prothrombin time (PT), serum total bilirubin, serum albumin content, main portal vein flow are significant factors. In the light of above variates contributing to grading liver function as to establish a discriminant equation, it was found that the total agreement rate between replaceable discrimination and original Child-Pugh classification is 86%. A test for agreement was performed between discriminant and original classification, showing that the two kinds of classification methods have a good agreement rates (Kappa = 0.7856), indicating the discriminant classification is of practical values.