Abstract
Biological condensates are now widely considered to be of fundamental biological, biomedical and biophysical importance. Numerous experimental studies suggest that bio-condensates like nucleolus, stress-granules, p-bodies etc. are physically underpinned to a significant degree by liquid-liquid phase separation (LLPS) of proteins driven by amino acid sequence pattern dependent multivalent interactions e.g. electrostatics, hydrophobicity, cation-Pi, Pi-Pi etc. The discovery of sequence dependent protein LLPS has led to the development of field-theoretic polymer physics models because mean field theories do not account fully for sequence specificity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
