Abstract

New organic pollutants such as pharmaceuticals have been recently classified as emerging pollutants.

Highlights

  • In recent decades environmental analysis has become of extensive interest to scientists, as new organic pollutants such as pharmaceuticals, personal care products, pesticides and polycyclic aromatic hydrocarbons are classi ed as emerging pollutants

  • The present work describes the development of the stir-bar sorptive extraction process and the new rapid analytical LCMS/MS method for determination of target pharmaceutical compounds

  • The developed method was critically evaluated in a set of 27 representative pharmaceuticals from a wide range of therapeutic classes, based on their occurrence in wastewater treatment plants (WWTPs) effluents and their suitability for stir-bar sorptive extraction (SBSE)

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Summary

Introduction

In recent decades environmental analysis has become of extensive interest to scientists, as new organic pollutants such as pharmaceuticals, personal care products, pesticides and polycyclic aromatic hydrocarbons are classi ed as emerging pollutants. Many of these are chemically active compounds that may pose a risk to environmental organisms as well as to humans.[1,2]. The polarity of the organic analyte roughly predicts the extraction efficiency. In addition to the KO/W, the phase ratio b (ratio of water sample volume, Vw) and volume of PDMS (VPDMS coated on stir bar) play key roles in the extraction efficiency (eqn (2))

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