Abstract
ObjectivesThe main objective of this study was to evaluate the pattern of altered pain processing in patients with chronic idiopathic neck pain, with particular emphasis on the interaction between pain sensitivity and modulation.MethodsThis cross-sectional study systematically evaluates patients with unilateral chronic idiopathic neck pain using a comprehensive, multi-modal quantitative sensory testing [QST] protocol. Only patients with unilateral idiopathic neck pain present without radicular symptoms for more than six months were invited to participate. The QST measurements consists of pressure pain threshold testing, thermal threshold testing, electrical pain threshold testing, wind-up response testing using electrical stimulation, and measurement of descending inhibitory modulation using the Conditioned Pain Modulation paradigm. For a control group, we randomly selected age- and gender-matched control values from our center database consisting of reference values of 118 pain-free healthy volunteers.Re...
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