Multi-level community interventions for primary stroke prevention: A conceptual approach by the World Stroke Organization.

Michael Brainin,Ralph Sacco,Valery Feigin,Epifania Collantes,Philip M Bath,Sheila Martins,Jeyaraj Pandian,Yvonne Teuschl

doi:10.1177/1747493019873706

Abstract

An effective primary stroke prevention strategy on a global scale should integrate pharmacological (polypill) and lifestyle modifications (motivational population-wide strategy) interventions. Side effects of such an integrative approach are expected to be minimal and the benefits among individuals at low-to-moderate risk of stroke could be significant. In the future, pragmatic field trials will provide more evidence.

Highlights

Stroke and dementia/cognitive impairment are the second most common causes of death and disability in the world.[1,2,3,4] In 2016, there were approximately 124 million people living with stroke and dementia worldwide, and every year stroke and dementia affect about 13.7 million and 7.8 million people, respectively.[1,2] The commonest outcome of cerebrovascular disease is not stroke, but cognitive impairment.[5]
The increasing burden of stroke and dementia emphasises the need for new, well-tolerated and cost-effective primary prevention strategies that can reduce the risks of stroke and dementia worldwide, and in low and middle-income countries (LMICs)
Over the last three decades stroke incidence and mortality rates in the world have decreased, the absolute number of people affected by stroke, died from or remained disabled from stroke as well as the absolute number of people with dementia has increased in all countries of the world.[1,2]

Summary

Introduction

Stroke and dementia/cognitive impairment are the second most common causes of death and disability in the world.[1,2,3,4] In 2016, there were approximately 124 million people living with stroke and dementia worldwide, and every year stroke and dementia affect about 13.7 million and 7.8 million people, respectively.[1,2] The commonest outcome of cerebrovascular disease is not stroke, but cognitive impairment.[5].

Results

Conclusion