Multi-Feature Automatic Extraction for Detecting Obstructive Sleep Apnea Based on Single-Lead Electrocardiography Signals.

Abstract

Obstructive sleep apnea (OSA), a prevalent sleep disorder, is intimately associated with various other diseases, particularly cardiovascular conditions. The conventional diagnostic method, nocturnal polysomnography (PSG), despite its widespread use, faces challenges due to its high cost and prolonged duration. Recent developments in electrocardiogram-based diagnostic techniques have opened new avenues for addressing these challenges, although they often require a deep understanding of feature engineering. In this study, we introduce an innovative method for OSA classification that combines a composite deep convolutional neural network model with a multimodal strategy for automatic feature extraction. This approach involves transforming the original dataset into scalogram images that reflect heart rate variability attributes and Gramian angular field matrix images that reveal temporal characteristics, aiming to enhance the diversity and richness of data features. The model comprises automatic feature extraction and feature enhancement components and has been trained and validated on the PhysioNet Apnea-ECG database. The experimental results demonstrate the model's exceptional performance in diagnosing OSA, achieving an accuracy of 96.37%, a sensitivity of 94.67%, a specificity of 97.44%, and an AUC of 0.96. These outcomes underscore the potential of our proposed model as an efficient, accurate, and convenient tool for OSA diagnosis.