Abstract

Objective To explore the impact of bundle prevention strategies on the CRBSI incidence.Methods Patients admitted to ICU with central venous catheter were given daily assessment and target monitor from 2008.2 to 2010.2,and divided into infected (117 cases) and non-infected ( 1 288 cases) group according to whether there was CRBSI.Analysis the relationship between the measures of bundle prevention strategies and the incidence of CRBSI,all data applications SPSS 10.0 for windows statistical software package for statistical analysis.Results In the study,1405 cases were collected,and 117 cases were infected while 1288 cases were non-infected.The total number of catheter day was 17 317 days,and the average was 12.85 d.Infection rate was 6.8 per 1 000 catheter days.Sex,age,type of skin plaster and time of changing skin plaster and infusion TPN were not different between the two groups (P>0.05).The single variable analysis has shown that the in the infection group,severity of clinical patients (APACHE Ⅱ > 20 points) was 78.63%,ICU stay time( > 30days) was 38.46%,emergency intubation method was 17.95%,patients received the frequency of invasive procedures( >4 times) was 83.76%,catheter day longer than 7 days was 78.63% were higher than those in the non-infection group (51.86%,15.53%,7.84%,35.02% and 31.13%,respectively) and the difference was significant ( x2 =8.071,23.750,10.781,36.56,44.886,respectively; P < 0.05 ) ; the pass rate of maximum sterile barrier (45.30%),the timeliness of joint disinfection on normal operation (68.38%) and catheterization in subclavian vein (40.17% ) in infection group were lower than non-infeclion group (75.93%,94.33% and 59.94%,respectively) and the difference was significant (x2 =9.303,4.604,5.076,respectively;P <0.05).Multiple regression analysis showed that the joint disinfection timeliness on normal operation was the independence factor of affecting CRBSI incidence ( OR =4.992,P < 0,01 ).Conclusions The implementation of bundle prevention strategies and strengthening the management of catheter connector can reduce the incidence of CRBSI. Key words: Bundle prevention strategies; Catheter-relatrd bloodstream infections; ICU; Influence factors

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