Multi-domain and multi-view networks model for clustering hospital admissions from the emergency department

Abstract

As the healthcare industry continues to generate a massive amount of medical data, healthcare organizations integrate data-driven insights into their clinical and operational processes to enhance the quality of healthcare services. Our preliminary hospital clustering analysis (Albarakati and Obradovic, in The IEEE 29th international symposium on computer-based medical systems (CBMS), IEEE, 2017) studied hospitals monthly admission behavior for different diseases. Results showed consistent behavior when disease symptoms similarity is considered. This study extends our preliminary work to include other aspects of disease data and the fusion of different views of disease data. It is an original approach that tackles clustering complex networks using a combination of multi-view and multi-domain clustering models while imposing data on the clustering goal from both medical and non-medical domains simultaneously. The objective of the study is to determine the effect of disease networks on characterizing the underlying clustering structure of 145 disease-specific hospital networks, each consisting of up to 152 hospitals. This is achieved by extracting two different views of disease networks. One disease network view based on similarity of symptom profiles was extracted from a 20 million medical bibliographic literature records. Another disease network view based on monthly hospitalization distribution was extracted from over 7 million discharge records data obtained from the California State Inpatient Database for years 2009–2011. Patient admission records included both medical and sociodemographic information. These multiple views were analyzed separately and were also integrated in a joint model that combined the two views. It is shown that the fusion of multi-view disease networks of monthly hospitalization distributions explained the hidden common structure shared among multiple hospital-specific disease networks. The group homogeneity measures for obtained hospital clusters ranged between 33 and 60% with average close to 50%. However, integrating multiple views of disease networks extracted from different domains, i.e., from literature and medical databases, better revealed the underlying clustering structure of disease-specific hospital networks. The group homogeneity measures for this multi-domain setting ranged between 38 and 76% with average close to 60%.