Abstract
Mucosal leishmaniasis (ML) is a chronic infection that affects the upper respiratory tract or oral mucosa and is caused by protozoan parasites of the genus Leishmania. A 94-year-old male presented with painful, multiple granulomatous lesions on the soft palate and oropharynx of 6 months duration. Extraoral clinical examination showed perforation of the anterior nasal septum. A biopsy of the oral lesion was taken, and microscopy revealed chronic inflammatory process. The specimen was also subjected to polymerase chain reaction and showed a 120-bp DNA fragment identical to that of Leishmania spp. A Montenegro skin test was positive. The final diagnosis was ML. The patient was referred to a medical service and was treated with liposomal amphotericin B at 2.5 g/day for 7 days. Financial support: FAPEMIG and CNPq.
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