Abstract
Mucormycosis is an aggressive and highly lethal pathology caused by an opportunistic fungus of the Mucorales order. Mucormycosis occurs particularly in patients with an impaired immune response. A 57-year-old woman with uncontrolled diabetes presented with palatal necrosis and hardening of the subcutaneous tissue at the level of the maxillary sinus associated with otalgia and myalgia. The patient was receiving antibiotic and antifungal therapy. The computed tomography (CT) exam showed gas bubbles in the left pterygopalatine fossa, originating from the extensive necrotic lesion of the palate and communication between these areas. The diagnostic hypotheses were squamous cells carcinoma and deep fungal infection, so the patient underwent incisional biopsy of the palatal lesion. The anatomopathologic exam revealed the presence of large nonseptate hyphae and intense infiltration of mixed inflammatory cells that were compatible with mucormycosis. The patient received amphotericin B therapy and was submitted to surgical resection of left hemiface and remains under follow-up. Support: FAPEMIG.
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