Abstract

IN the absence of acute infection, the excessive bronchial secretion in chronic bronchitis is mucoid and owes its viscidity to a gel structure. This is apparent as an oriented fibrous network in the polarizing and electron microscopes1–3, and there is a yield-value for disruption of the gel2–4. Mucoprotein can be isolated in yields of about 60 per cent of the total nitrogen by the procedure of Curtain and Pye5, and has the composition shown in Table 1. Mannose and galactose are also constant constituents1–3.

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