Abstract
Gall bladder carcinoma is the most common type of tumor of the biliary tract and adenocarcinoma is the major histopathological subtype. Mucinous variant is a rare subtype and mucinous carcinoma accompanied with signet ring is extremely rare. When mucinous component exceeds 90% of the tumor, it is labeled as pure mucinous carcinoma. Immunohistochemistry helps to distinguish primary mucinous adenocarcinoma of gall bladder from pseudo myxoma peritonei from appendiceal neoplasm. Mucinous carcinoma is CK 7 positive and CK20 negative. We report a case of mucinous adenocarcinoma arising from the fundus of the gall bladder.
 Keywords: Mucinous carcinoma, Gall bladder, Adenocarcinoma, Metastatic deposits
Highlights
Extracellular mucin production in various carcinomas has been shown to reflect activation or modification of a variety of cellular pathways that impart a different morphology to the tumor and present distinct biological properties of the tumor cells (1)
When mucinous component exceeds 90% of the tumor, it is labeled as pure mucinous carcinoma (3)
We report a case of mucinous adenocarcinoma arising from the fundus of the gall bladder
Summary
Extracellular mucin production in various carcinomas has been shown to reflect activation or modification of a variety of cellular pathways that impart a different morphology to the tumor and present distinct biological properties of the tumor cells (1). Gall bladder carcinoma is the most common type of tumor of the biliary tract and adenocarcinoma is the major histopathological subtype. Mucinous variant is a rare subtype and mucinous carcinoma (MC) accompanied with signet ring is extremely rare (2). When mucinous component exceeds 90% of the tumor, it is labeled as pure mucinous carcinoma (3).
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