Mu rhythm suppression reflects mother-child face-to-face interactions: a pilot study with simultaneous MEG recording.

Chiaki Hasegawa,Mitsuru Kikuchi,Yuko Yoshimura,Masayuki Hirata,Naoki Furutani,Tetsuya Takahashi,Hirotoshi Hiraishi,Yoshio Minabe,Takashi Ikeda,Norio Hayashi,Minoru Asada

doi:10.1038/srep34977

Chiaki Hasegawa, Mitsuru Kikuchi + Show 9 more

Open Access

https://doi.org/10.1038/srep34977

Copy DOI

Abstract

Spontaneous face-to-face interactions between mothers and their children play crucial roles in the development of social minds; however, these inter-brain dynamics are still unclear. In this pilot study, we measured MEG mu suppression during face-to-face spontaneous non-linguistic interactions between mothers and their children with autism spectrum disorder (ASD) using the MEG hyperscanning system (i.e., simultaneous recording). The results demonstrated significant correlations between the index of mu suppression (IMS) in the right precentral area and the traits (or severity) of ASD in 13 mothers and 8 children (MEG data from 5 of the children could not be obtained due to motion noise). In addition, higher IMS values (i.e., strong mu suppression) in mothers were associated with higher IMS values in their children. To evaluate the behavioral contingency between mothers and their children, we calculated cross correlations between the magnitude of the mother and child head-motion during MEG recordings. As a result, in mothers whose head motions tended to follow her child’s head motion, the magnitudes of mu suppression in the mother’s precentral area were large. Further studies with larger sample sizes, including typically developing children, are necessary to generalize this result to typical interactions between mothers and their children.

Highlights

Spontaneous face-to-face interactions between mothers and their children play crucial roles in the development of social minds; these inter-brain dynamics are still unclear
Given that the soundness of social minds are reflected in the degree of mu suppression, the dynamics of mu rhythms during real communication between mothers and their children might serve as an index of soundness in brain-to-brain interactions
In children (Table S1), Spearman’s rank correlation analysis failed to reveal any significant correlation between the index of mu suppression (IMS) and any indices of cross correlation coefficients (p > 0.05). This is the first study to demonstrate that the degree of mu suppression during face-to-face spontaneous, non-linguistic mother-child interactions is negatively correlated with the degree of autistic traits in the mother and with symptom severity in children with autism spectrum disorder (ASD)

Summary

Introduction

Spontaneous face-to-face interactions between mothers and their children play crucial roles in the development of social minds; these inter-brain dynamics are still unclear. In this pilot study, we measured MEG mu suppression during face-to-face spontaneous non-linguistic interactions between mothers and their children with autism spectrum disorder (ASD) using the MEG hyperscanning system (i.e., simultaneous recording). Typically developed mothers and their young children with ASD (with various levels of social ability) were included to test a high diversity of mother-child interactions These mother-child interactions are not typical, we believed a larger diversity of participants would better reveal the neural correlates of social behavior

Objectives

Methods

Results

Conclusion