Abstract

Aiming at the limitation of the convolution kernel with a fixed receptive field and unknown prior to optimal network width in U-Net, multi-scale U-Net (MSU-Net) is proposed by us for medical image segmentation. First, multiple convolution sequence is used to extract more semantic features from the images. Second, the convolution kernel with different receptive fields is used to make features more diverse. The problem of unknown network width is alleviated by efficient integration of convolution kernel with different receptive fields. In addition, the multi-scale block is extended to other variants of the original U-Net to verify its universality. Five different medical image segmentation datasets are used to evaluate MSU-Net. A variety of imaging modalities are included in these datasets, such as electron microscopy, dermoscope, ultrasound, etc. Intersection over Union (IoU) of MSU-Net on each dataset are 0.771, 0.867, 0.708, 0.900, and 0.702, respectively. Experimental results show that MSU-Net achieves the best performance on different datasets. Our implementation is available at https://github.com/CN-zdy/MSU_Net.

Highlights

  • Medical imaging analysis has made a significant breakthrough with the rapid progress of deep learning (Long et al, 2015; Chen et al, 2018a; Salehi et al, 2018; Wang et al, 2019b)

  • Our results demonstrate that multi-scale U-Net (MSU-Net) built by integrated multiple convolution sequences with different receptive fields enables significant improvement of semantic segmentation

  • 31 kinds of multi-scale blocks were designed by combining the convolution kernel with different receptive fields

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Summary

Introduction

Medical imaging analysis has made a significant breakthrough with the rapid progress of deep learning (Long et al, 2015; Chen et al, 2018a; Salehi et al, 2018; Wang et al, 2019b). Among these techniques, encoder-decoder architecture has been widely used in the medical image segmentation task (Salehi et al, 2017; Xiao et al, 2018; Guan et al, 2019). Redundant features will be extracted when the receptive field of the convolution kernel is too small. It is very important to use the convolution kernel with different

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