Abstract

De novo drug development is an extremely time-consuming process with a high risk of failure and tremendous resource requirements. For these reasons, a drug-repurposing strategy has gained significant attention as a cost-effective alternative strategy. Drug repurposing can rapidly repurpose FDA-approved drugs to other indications than the approved indications. Until now, drug repurposing is serendipitous, such as repurposing Sildenafil for erectile dysfunction, and sometimes requires extensive manual reviews of related literature, clinical trials, and relevant clinical data. With an ever-growing amount of literature and information, an automatic method is much needed.

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