Abstract
Colorectal cancer can serve as an excellent model for cancer prevention. Tumors start as early premalignant lesions, easy to detect and remove, progress over adenoma with a varying degree of atypia into carcinomas [1]. Thus, early detection is possible and of major importance in reducing the morbidity and mortality in colorectal cancer. During the last decade much new knowledge has come to light concerning the hereditary forms of colorectal cancer. The number of individuals participating in prevention programs is increasing and includes healthy high-risk individuals [2,3]. These prevention programs comprise genetic counseling and when possible, predictive genetic testing. Regular colonoscopies provided for high-risk individuals have resulted in decreased incidence of and mortality from colorectal cancer [4]. This surveillance is well tolerated and understood by those included in these preventive programs [5].
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