Abstract

Interdisciplinary translational research between physiologists and clinicians based on mRNA technology has opened and shall open treatment perspectives for a broad range of diseases, many of them hitherto hard to treat or not treatable at all. In this overview, various options for applications of mRNA technology are presented for the treatment of quite different neurological and neuro-ophthalmological disease categories such as metabolic and neurodegenerative diseases, infectious diseases, and tumors, illustrated by a few selected examples of current clinical trials and experimental approaches. mRNA technology allows for developing tailor-made individualized therapies by which the body may even produce the remedies itself according to the physiological recipe of the mRNA assembly instructions.

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