Abstract
The use of efficient treatment with a treat-to-target strategy combined with early detection of the disease completely changed the imaging presentation and outcome of newly diagnosed rheumatoid arthritis (RA) patients. Magnetic Resonance Imaging (MRI) has become the reference technique in clinical research to detect and quantify inflammatory involvement of the soft tissues (synovitis and tenosynovitis) and bone marrow (osteitis) along with structural damages of the bone (erosions) in hands of patients with RA. Three-point Dixon MRI may be a valuable alternative to the currently recommended sequences as it yields effective fat signal suppression, high imaging quality and reproducible assessment of disease activity.
Highlights
The current article aims to depict the evolution of rheumatoid arthritis (RA) imaging in the last decades and the potential advantages of Dixon Magnetic Resonance Imaging (MRI) sequences in the quantitative assessment of early RA disease activity in hands with the Rheumatoid Arthritis MRI scoring system (RAMRIS)
RAMRIS first included the scoring of synovitis, osteitis, and erosions with addition of tenosynovitis and cartilage loss in 2016 [32, 33]
Fat suppression is essential in musculoskeletal MRI as it allows better detection of lesions with increased water content on T2-weighted images and better detection of enhancing tissue on T1-weighted images after intravenous gadolinium-based contrast-material injection
Summary
The current article aims to depict the evolution of rheumatoid arthritis (RA) imaging in the last decades and the potential advantages of Dixon Magnetic Resonance Imaging (MRI) sequences in the quantitative assessment of early RA disease activity in hands with the Rheumatoid Arthritis MRI scoring system (RAMRIS)
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