MRI feature tracking strain profiles distinguish patients with left ventricular systolic and diastolic dysfunction with and without clinical heart failure

Naila Choudhary,Alistair Young,Lynette J Duncanson,Javed Butler,Nathaniel Reichek,Jie J Cao,Timothy Vittorio

doi:10.1186/1532-429x-18-s1-o79

Abstract

Background Characterizing myocardial mechanical properties is valuable in understanding cardiomyopathy with and without clinical heart failure (HF). We sought to examine the incremental value of strain assessment in patients with left ventricular systolic dysfunction without HF (LVSD), HF with reduced ejection fraction (HFrEF), LV diastolic dysfunction without HF (LVDD) and HF with preserved EF (HFpEF) during routine cardiac MR (CMR) evaluation.

Highlights

Characterizing myocardial mechanical properties is valuable in understanding cardiomyopathy with and without clinical heart failure (HF)
We sought to examine the incremental value of strain assessment in patients with left ventricular systolic dysfunction without HF (LVSD), HF with reduced ejection fraction (HFrEF), LV diastolic dysfunction without HF (LVDD) and HF with preserved EF (HFpEF) during routine cardiac MR (CMR) evaluation
The early diastolic relaxation rate in the circumferential direction dropped by ~50% in HFrEF and LVSD but it was largely unchanged in HFpEF and LVDD

Summary

Background

Characterizing myocardial mechanical properties is valuable in understanding cardiomyopathy with and without clinical heart failure (HF). We sought to examine the incremental value of strain assessment in patients with left ventricular systolic dysfunction without HF (LVSD), HF with reduced ejection fraction (HFrEF), LV diastolic dysfunction without HF (LVDD) and HF with preserved EF (HFpEF) during routine cardiac MR (CMR) evaluation

Methods

Conclusions

Results