Abstract

Magnetic resonance imaging (MRI) compatibility of three early transition metal (ETM) based alloys was assessed in vitro with agarose gel as a phantom, including Zr-20Nb, near-equiatomic (TiZrNbTa)90 Mo10 and Nb-60Ta-2Zr, together with pure tantalum and L605 Co-Cr alloy for comparison. The artifact extent in the MR image was quantitatively characterized according to the maximum area of 2D images and the total volume in reconstructed 3D images with a series of slices under acquisition by fast spin echo (FSE) sequence and gradient echo (GRE) sequence. It was indicated that the artifacts extent of L605 Co-Cr alloy with a higher magnetic susceptibility (χv ) was approximately 3-fold greater than that of the ETM-based alloys with χv in the range of 160-250 ppm. In the ETM group, the MRI compatibility of the materials can be ranked in a sequence of Zr-20Nb, pure tantalum, (TiZrNbTa)90 Mo10 and Nb-60Ta-2Zr. In addition, using a rabbit cadaver with the implanted tube specimens as a model for ex vivo assessment, it was confirmed that the artifact severity of Nb-60Ta-2Zr alloy is significantly reduced in comparison with the L605 alloy. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 377-385, 2018.

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