Abstract

Background Current treatment guidelines recommend surgical bypass for peripheral chronic total occlusions (CTOs)[1]. Percutaneous transluminal angioplasty (PTA), however, offers a less invasive approach with improved perioperative morbidity, shorter length of hospital stay, and lower cost[2]. Not all lesions are amenable to this technique and there is a significant primary failure rate[2]. Predicting lesion crossability is difficult because current imaging techniques offer limited information with which to characterize CTOs. The ability to distinguish between hard and soft biological substances that compose a CTO can aid procedural planning and facilitate intervention. This pilot study demonstrates the ability of high resolution MRI to characterize peripheral CTO components with microCT and histologic validation.

Highlights

  • Current treatment guidelines recommend surgical bypass for peripheral chronic total occlusions (CTOs)[1]

  • MRI was performed on 10 excised human peripheral arterial CTO segments from 3 patients

  • A difference image was produced by subtracting the complex signal values of the 1ms-image from those of the 20μs-image

Read more

Summary

Introduction

Current treatment guidelines recommend surgical bypass for peripheral chronic total occlusions (CTOs)[1]. Methods MRI was performed on 10 excised human peripheral arterial CTO segments from 3 patients. Imaging system) at high resolution (75x75x75μm voxels) to produce three-dimensional T2- and T2*weighted images.

Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call