MRC/BHF Heart Protection Study

Abstract

LetterMarch 1, 2003MRC/BHF Heart Protection StudyC. R. Kumana, FRCP, B. M. Cheung, FRCP, I. J. Lauder, PhDC. R. Kumana, FRCPUniversity of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)Search for more papers by this author, B. M. Cheung, FRCPUniversity of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)Search for more papers by this author, I. J. Lauder, PhDUniversity of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2003-138-2-A15 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinkedInRedditEmail Additional Information from CommentatorsIn our commentary on the summary of the Heart Protection Study (HPS) in the January/February 2003 issue of ACP Journal Club (1), a table germane to our discussion had to be omitted due to space constraints and was replaced with a notation referring readers to the table on the Web site. We thank the editors for allowing us to reproduce the table below.Regarding the HPS, derivation of the corresponding NNT/year and 95% CI for prevention of CHD events gives very similar values (165, CI 130 to 230) to those for patients in the CARE and LIPID trials. ...References1 Kumana CR, Cheung BM, Lauder IJ. Commentary on “Simvastatin reduced mortality and vascular events in high-risk patients” and “Antioxidant vitamins did not reduce death, vascular events, or cancer in high-risk patients.” ACP J Club. 2003 Jan-Feb;138:2-3. [PMID: 12511114] Comment on: MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomized placebo-controlled trial. Lancet. 2002;360:7-22 and MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomized placebo-controlled trial. Lancet. 2002;360:23-33. Google Scholar2 Kumana CR, Cheung BM, Lauder IJ. Gauging the impact of statins using number needed to treat. JAMA. 1999;282:1899-901. [PMID: 10580441] Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.)University of Hong Kong, Hong Kong, China (C.R.K., B.M.C., I.J.L.) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSimvastatin reduced mortality and vascular events in high-risk patients B.M. Cheung , C.R. Kumana , and I.J. Lauder Antioxidant vitamins did not reduce death, vascular events, or cancer in high-risk patients B.M. Cheung , C.R. Kumana , and I.J. Lauder March 1, 2003Volume 138, Issue 2Page: A15 ePublished: 9 March 2020 Issue Published: March 1, 2003 Copyright & PermissionsCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...