MR urogram findings and diffusion restriction in the renal papilla and calyx in papillary necrosis-a new finding: preliminary report.

Abstract

Renal papillary necrosis is a clinicopathological entity where any or all of the papillae undergo selective necrosis, which can be demonstrated either radiologically or histologically. The most important causes are diabetes, pyelonephritis, obstructive uropathy, tuberculosis, analgesic abuse or overuse, sickle cell disease and renal vein thrombosis. Although this condition was first described in the 19th century the clinical diagnosis of this condition remains a problem to this day. Uncomplicated papillary necrosis may initially remain occult to imaging by ultrasound and non-contrast CT, but may later be complicated by obstructive uropathy. A few studies have described renal papillary necrosis on CT urogram. In this case series, the authors describe the finding of calyceal filling defect with diffusion restriction in the calyx and the tip of the renal pyramid on MR urogram, along with other findings that are classically seen on intravenous urogram or CT urogram. To the best of our knowledge, the finding of diffusion restriction at the tip of the renal pyramid has not been described before. Further, literature review showed only a single study describing the classical findings of papillary necrosis on an MR urogram. The early diagnosis of papillary necrosis on MR imaging equips the radiologist to suggest short-term clinical and radiological follow-up to check for the development of hydronephrosis. Additionally, such risk stratification may enable early ureteric stenting to prevent the development of obstructive uropathy.