Abstract

The aim of the study was to compare the volumes according to MR morphometry and diffusion values according to diffusion-tensor MRI (DT-MRI) of the corpus callosum in children with spastic diplegia. Methods: the main group consisted of 12 children aged from 1 year 8 months to 4 years 3 months, the comparison group — 5 children with normal motor development, who did not have motor impairments, at the age from 1 year and 3 months up to 3 years 8 months. All patients underwent MR-morphometry, DTI. A comparison was made between the volumes and diffusion values of the corpus callosum between groups. Results: Significant differences were found (p<0,05) in the volume of the genu, splenium and the middle third of the trunk of the corpus callosum. Significant differences (p<0,05) of diffusion values in the middle and posterior third of the trunk of the corpus callosum were also revealed. The data obtained demonstrate the diffuse nature of pathological changes in the corpus callosum in children with spastic diplegia.

Highlights

  • Целью исследования являлась сравнительная оценка объема мозолистого тела по данным МР-морфометрии и показателей диффузии в мозолистом теле по данным диффузионно-тензорной МРТ (ДТ-МРТ) у детей со спастической диплегией

  • The aim of the study was to compare the volumes according to MR morphometry and diffusion values according to diffusion-tensor MRI (DT-MRI) of the corpus callosum in children with spastic diplegia

  • A comparison was made between the volumes and diffusion values of the corpus callosum between groups

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Summary

Introduction

МР МОРФОМЕТРИЯ И ДИФФУЗИОННО ТЕНЗОРНАЯ МРТ В ОЦЕНКЕ ИЗМЕНЕНИЙ МОЗОЛИСТОГО ТЕЛА У ДЕТЕЙ Целью исследования являлась сравнительная оценка объема мозолистого тела по данным МР-морфометрии и показателей диффузии в мозолистом теле по данным диффузионно-тензорной МРТ (ДТ-МРТ) у детей со спастической диплегией. Результаты: выявлены достоверные различия (p

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