MR Imaging of Non-Traumatic Intrinsic Brachial Plexus Neuropathy: Spectrum of Findings

Abstract

Objective: Non-traumatic intrinsic neuropathy of the brachial plexus (BP) could be because of focal or diffuse involvement. The purpose of this article is to focus on MR imaging spectrum and illustrate key features of a variety of pathologic entities based on review of 21 imaging studies. This paper highlights the detailed MR anatomy, the imaging techniques and the spectrum of MR imaging appearances of focal and diffuse form of non-traumatic intrinsic brachial neuropathy. Materials and methods: We retrospectively reviewed 140 consecutive BP MR examinations performed at our institution over a period of four years from August 2006 to August 2010. We excluded cases of diverse clinical data including both traumatic and non-traumatic extrinsic compressive brachial neuropathies occuring along the course of the BP. Of 140 MR imaging studies of the BP, 75 were excluded and remaining 65 imaging studies were included for review. BP was assessed for the calibre, continuity, presence and distribution of signal changes (focal or diffuse) and focal masses. Results: 21 of the 65 included imaging studies showed features of non-traumatic intrinsic BP neuropathy. The diagnosis was made on the basis of MR findings, electromyographic (EMG), clinical patient information and histopathological findings. The diagnosis included spectrum of neoplastic and non-neoplastic conditions like perineurioma, radiation plexitis, chronic inflammatory demyelinating polyneuropathy (CIDP) and hereditary motor sensory neuropathy (HMSN).