MP97-09 VENOUS THROMBOEMBOLIC EVENTS IN PATIENTS UNDERGOING OPEN AND MINIMALLY INVASIVE RADICAL PROSTATECTOMY: POPULATION-BASED TIME TREND ANALYSIS

Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy VIII1 Apr 2017MP97-09 VENOUS THROMBOEMBOLIC EVENTS IN PATIENTS UNDERGOING OPEN AND MINIMALLY INVASIVE RADICAL PROSTATECTOMY: POPULATION-BASED TIME TREND ANALYSIS Raisa Sinaida Pompe, Emanuele Zaffuto, Helen Davis Bondarenko, Zhe Tian, Jonas Schiffmann, Sami-Ramzi Leyh-Bannurah, Hartwig Huland, Markus Graefen, Derya Tilki, and Pierre I. Karakiewicz Raisa Sinaida PompeRaisa Sinaida Pompe More articles by this author , Emanuele ZaffutoEmanuele Zaffuto More articles by this author , Helen Davis BondarenkoHelen Davis Bondarenko More articles by this author , Zhe TianZhe Tian More articles by this author , Jonas SchiffmannJonas Schiffmann More articles by this author , Sami-Ramzi Leyh-BannurahSami-Ramzi Leyh-Bannurah More articles by this author , Hartwig HulandHartwig Huland More articles by this author , Markus GraefenMarkus Graefen More articles by this author , Derya TilkiDerya Tilki More articles by this author , and Pierre I. KarakiewiczPierre I. Karakiewicz More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.3053AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The rate of venous thromboembolic events (VTE) after open (ORP) or minimally invasive radical prostatectomy (MIRP) for prostate cancer (PCa) might be decreasing over the last decade. The aim of the present study was to assess the 30- and 90-day VTE rates and mortality over time. METHODS Using the Surveillance Epidemiology and End results (SEER)- Medicare database, we identified 35104 nonmetastatic PCa patients who underwent RP between 1994 and 2009. The annual incidence rates of VTE and mortality were analyzed over the observation period. The estimated annual percentage change (EAPC) was calculated using the least squares log linear regression method. Based on stepwise selection, risk factors for VTE were identified. Multivariable logistic regression models were performed to test the effect of these variables on VTE rates. RESULTS At 30 days after RP, 931 (2.7%) VTE and 87 (0.25%) deaths were recorded. Additionally, at 90-days, 1112 (3.2%) VTE and 121 (0.3%) deaths were registered. Over a period of 15 years, annual 30-day VTE and mortality rates decreased from 3.5% to 2.2% and from 0.4% to 0.2%, respectively. Similarly, 90-day VTE and mortality rates decreased from 4.2% to 2.7% and from 0.6% to 0.3%. Independent VTE-risk factors consisted of older age, longer hospital stay, pelvic lymph node dissection (PLND) and blood transfusions. In multivariable analysis, prostatectomy type (ORP or MIRP) did not affect VTE or mortality rates. CONCLUSIONS Although, VTE are rare complications, they may result in patient demise. In consequence, patients with one or multiple risk factors should be targeted with preventive strategies. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1306 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Raisa Sinaida Pompe More articles by this author Emanuele Zaffuto More articles by this author Helen Davis Bondarenko More articles by this author Zhe Tian More articles by this author Jonas Schiffmann More articles by this author Sami-Ramzi Leyh-Bannurah More articles by this author Hartwig Huland More articles by this author Markus Graefen More articles by this author Derya Tilki More articles by this author Pierre I. Karakiewicz More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...