MP89-03 NORMAL PREOPERATIVE FOLLICLE-STIMULATING HORMONE LEVEL IS ASSOCIATED WITH IMPROVEMENT IN SEMEN PARAMETERS FOLLOWING MICROSURGICAL VARICOCELECTOMY

Abstract

You have accessJournal of UrologyInfertility: Therapy I1 Apr 2017MP89-03 NORMAL PREOPERATIVE FOLLICLE-STIMULATING HORMONE LEVEL IS ASSOCIATED WITH IMPROVEMENT IN SEMEN PARAMETERS FOLLOWING MICROSURGICAL VARICOCELECTOMY Lunan Ji, Samuel A. Shabtaie, Nachiketh Soodana Prakash, and Ranjith Ramasamy Lunan JiLunan Ji More articles by this author , Samuel A. ShabtaieSamuel A. Shabtaie More articles by this author , Nachiketh Soodana PrakashNachiketh Soodana Prakash More articles by this author , and Ranjith RamasamyRanjith Ramasamy More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2801AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We investigated whether preoperative follicle-stimulating hormone (FSH) level is associated with changes in postoperative semen parameters following microsurgical varicocelectomy. METHODS We identified 37 men who had undergone microsurgical varicocelectomy between August 2015 and June 2016. We compared semen parameters in men based on their preoperative FSH level, defined as normal <10 mIU/ml (n=25) and abnormal =>10 mIU/ml (n=12). We compared varicocele grade, testis volume, prevalence of bilateral disease, preoperative, and postoperative semen parameters (at 3 months) between men with normal and abnormal FSH. RESULTS The age, varicocele grade, preoperative testosterone levels were similar between men who underwent microsurgical varicocelectomy with normal and high FSH. Men with higher FSH had higher rates of bilateral disease. In a univariate analysis, men with FSH <10 mIU/mL had higher increases in absolute total sperm count (20.4M vs. 0.8M, p=0.002), sperm concentration (5.2M/mL vs. 1.4M/mL, p=0.05), and total motile count (5.1M vs. 1.4M, p=0.02) postoperatively compared to those with abnormal FSH. As expected, testis volume was smaller in the men with high FSH (12 cc vs. 14 cc, p=0.004). Change in motility was not significantly different between men with abnormal and normal FSH. CONCLUSIONS Our study suggested an association between men with normal FSH levels (<10 mIU/ml) and significant improvements in total sperm count, sperm concentration, and total motile count among those who underwent microscopic varicocelectomy. Normal FSH levels can suggest preserved spermatogenesis and greater improvement in semen parameters following varicocele repair. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1203 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Lunan Ji More articles by this author Samuel A. Shabtaie More articles by this author Nachiketh Soodana Prakash More articles by this author Ranjith Ramasamy More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...