MP86-13 HEALTH RELATED QUALITY OF LIFE OF PATIENTS UNDERGOING ACTIVE SURVEILLANCE – COMPARISON WITH PROSTATE CANCER ACTIVE TREATMENTS

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Quality of Life and Shared Decision Making V1 Apr 2017MP86-13 HEALTH RELATED QUALITY OF LIFE OF PATIENTS UNDERGOING ACTIVE SURVEILLANCE – COMPARISON WITH PROSTATE CANCER ACTIVE TREATMENTS Lluis Fumado, Jose Francisco Suárez, Olatz Garín, Andrea Sureda, Montse Ferrer, Manel Castells, Jose Maria Abascal, Maria Carme Mir, Xavier Bonet, Helena Vila, Lluís Cecchini, and Francesc Vigués Lluis FumadoLluis Fumado More articles by this author , Jose Francisco SuárezJose Francisco Suárez More articles by this author , Olatz GarínOlatz Garín More articles by this author , Andrea SuredaAndrea Sureda More articles by this author , Montse FerrerMontse Ferrer More articles by this author , Manel CastellsManel Castells More articles by this author , Jose Maria AbascalJose Maria Abascal More articles by this author , Maria Carme MirMaria Carme Mir More articles by this author , Xavier BonetXavier Bonet More articles by this author , Helena VilaHelena Vila More articles by this author , Lluís CecchiniLluís Cecchini More articles by this author , and Francesc ViguésFrancesc Vigués More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2696AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Active surveillance in localised prostate cancer is an accepted option in selected cases, but some concerns still needs to be clarified. We pretend to evaluate Health-Related Quality of Life (HRQoL), in a cross-sectional study, in patients with localized prostate cancer undergoing active surveillance (AS) compared with active treatments (radical prostatectomy, external-beam radiotherapy, brachytherapy) and general population. METHODS Ninety-nine patients fulfilled the inclusion criteria. This group was compared to different active treatments (n=99 per group) from the 'Spanish Multicentric Study of Clinically Localized Prostate Cancer' cohort using prostate-specific (Expanded Prostate Cancer Index Composite [EPIC]) and generic (36-Item Short Form Health Survey, version 2 [SF-36]) QoL instruments. SF-36 results were also compared to US reference population. RESULTS Cross-section analysis was performed at 24 months after initial therapy or AS beginning. AS group presented statistically higher sexual scores [54.4 mean score (28.3 SD)] when compared to all other active treatments and better urinary incontinence scores [87.4 (22.8 SD)] than radical prostatectomy group [65.8 (31.6 SD)]. Patients undergoing AS were more likely to present significant urinary irritative/obstructive symptoms compared to radical prostatectomy group. No statistically significant differences were found among other domains. Patients with localized prostate cancer, regardless of treatment applied, presented slightly higher SF-36 physical and mental dimension scores (except for radical prostatectomy) than US general population reference norm (men aged 65-74). CONCLUSIONS AS may be a good treatment option for low or intermediate risk prostate cancer since induces the least impact in QoL. No significant differences were found on Physical and Mental Component Summaries compared to general US population. This study provides cross-sectional information about AS impact on QoL. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1161 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Lluis Fumado More articles by this author Jose Francisco Suárez More articles by this author Olatz Garín More articles by this author Andrea Sureda More articles by this author Montse Ferrer More articles by this author Manel Castells More articles by this author Jose Maria Abascal More articles by this author Maria Carme Mir More articles by this author Xavier Bonet More articles by this author Helena Vila More articles by this author Lluís Cecchini More articles by this author Francesc Vigués More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...