MP86-10 RELATIONSHIP BETWEEN OVERACTIVE BLADDER AND METABOLIC SYNDROME: A CROSS-SECTIONAL STUDY AMONG JAPANESE MEN AND WOMEN.

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Quality of Life and Shared Decision Making V1 Apr 2017MP86-10 RELATIONSHIP BETWEEN OVERACTIVE BLADDER AND METABOLIC SYNDROME: A CROSS-SECTIONAL STUDY AMONG JAPANESE MEN AND WOMEN. Yoshitaka Aoki, Chieko Matsumoto, Yosuke Matsuta, Hideaki Ito, Yukinori Kusaka, and Osamu Yokoyama Yoshitaka AokiYoshitaka Aoki More articles by this author , Chieko MatsumotoChieko Matsumoto More articles by this author , Yosuke MatsutaYosuke Matsuta More articles by this author , Hideaki ItoHideaki Ito More articles by this author , Yukinori KusakaYukinori Kusaka More articles by this author , and Osamu YokoyamaOsamu Yokoyama More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2693AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Metabolic syndrome (MetS) has been implicated in the aetiology of lower urinary symptoms and a few previous epidemiological studies have suggested a relationship between MetS and overactive bladder (OAB) in women. We thus aimed to evaluate the relationship between OAB and MetS or components of MetS among Japanese men and women. METHODS We collected data on 12,478 individuals (5,313 males and 7,165 females) who participated in a multiphasic health screening in 2015, in Fukui, Japan. As part of a multiphasic health screening, waist circumference, blood pressure, fasting blood sugar, triglycerides and HDL-cholesterol were measured. All participants were asked to answer a standardized self-reported questionnaire for OAB screening (SQOAB, Screening Questionnaire for Overactive Bladder) [Int J Urol, 2009].We analyzed the relationships between OAB and other variables including age, gender, waist circumference, high blood pressure, impaired glucose tolerance, and dyslipidemia. The relationships between OAB and MetS were also analyzed. MetS in the Japanese criteria was diagnosed in individuals who had a high waist circumference (≥ 85 cm in men and ≥ 90 cm in women) plus any 2 of the following: (a) high blood pressure (systolic blood pressure ≥ 130/85 mmHg and/or current use of antihypertensive medicine); (b) impaired glucose tolerance (fasting glucose concentration ≥ 110 mg/dL and/or current use of antidiabetic medication); and (c) dyslipidemia (triglyceride concentration ≥ 150 mg/dL and/or HDL-cholesterol level < 40 mg/dL). The chi-square test and logistic regression modeling were used for statistical analyses. Values of p<0.05 were considered statistically significant. RESULTS The median age of participants was 69 (18-95) years. The overall prevalence of OAB and MetS were 13.5% (11.2% for men and 15.2% for women) and 15.2% (24.5% for men and 8.2% for women), respectively. The prevalence was higher in older age groups. A significant association was found between OAB and MetS The age-adjusted odds ratio (95% CI) were 1.22 (1.06-1.39) for men and 1.49 (1.21-1.83) for women, respectively. We also analyzed the relationships between OAB and the number of components of MetS. In the multivariate analysis, a significant association was found between OAB and the following: age (odds ratio = 1.05) and high waist circumference (1.24) for men, and, age (1.04) , high waist circumference (1.42) and hyperglycemia (1.17) for women. CONCLUSIONS Our study confirmed the relationship between OAB and MetS in both men and women. These findings suggest that OAB is a facet of the MetS. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1160 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Yoshitaka Aoki More articles by this author Chieko Matsumoto More articles by this author Yosuke Matsuta More articles by this author Hideaki Ito More articles by this author Yukinori Kusaka More articles by this author Osamu Yokoyama More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...