MP84-14 THE IMPACT OF MICRO-METASTATIC PELVIC LYMPH NODE INVOLVEMENT ON 3 YEAR SURVIVAL IN SQUAMOUS CELL CARCINOMA OF THE PENIS

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Penis/Testis/Urethra: Benign Disease & Malignant Disease II1 Apr 2018MP84-14 THE IMPACT OF MICRO-METASTATIC PELVIC LYMPH NODE INVOLVEMENT ON 3 YEAR SURVIVAL IN SQUAMOUS CELL CARCINOMA OF THE PENIS Benjamin Ayres, Rami Issa, Alison Tree, Brendan Tinwell, Cathy Corbishley, and Nick Watkin Benjamin AyresBenjamin Ayres More articles by this author , Rami IssaRami Issa More articles by this author , Alison TreeAlison Tree More articles by this author , Brendan TinwellBrendan Tinwell More articles by this author , Cathy CorbishleyCathy Corbishley More articles by this author , and Nick WatkinNick Watkin More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2782AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Achieving complete ipsilateral pathological pelvic nodal staging has become more feasible in penile cancer patients (SCCp) with inguinal nodal extracapsular spread (ipN3) due to reduced morbidity with minimally invasive surgery. We prospectively analysed the micro-metastatic pelvic node yield in completely staged men and calculated survival curves. METHODS Data was collected prospectively. Survival was calculated using Kaplan Meier analysis. All cases were discussed at a supranetwork multidisciplinary meeting. Adjuvant chemoradiotherapy was planned for any groin with extracapsular spread or pelvis with positive nodes. RESULTS Since January 2012, 31 men with SCCp, ipN3 but pelvic node negative on CT, underwent complete pathological pelvic node staging. Median age was 59 years (IQR 54-67). Median node yield was 8 (IQR 6-10). 94% were performed robotically. 84% received adjuvant chemoradiotherapy.52% of men had micro-metastatic disease in at least 1 ipsilateral pelvic node. Comparison of 3-year overall survival of negative pelvic node dissection vs positive pelvic node dissection showed similar survival curves plateauing at around 18 months. 3-year overall survival was 69% vs 65% respectively. CONCLUSIONS A significant number of men had micro-metastatic pelvic node involvement. The explanation behind similar survival curves is uncertain but highlights the importance of complete pathological nodal staging which determines the extent of adjuvant therapy. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1130 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Benjamin Ayres More articles by this author Rami Issa More articles by this author Alison Tree More articles by this author Brendan Tinwell More articles by this author Cathy Corbishley More articles by this author Nick Watkin More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...