MP82-04 DOES NIGHT TIME 12 HOUR URINE COLLECTION CORRELATE TO 24 HOUR URINE COLLECTION?

Abstract

You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation I1 Apr 2016MP82-04 DOES NIGHT TIME 12 HOUR URINE COLLECTION CORRELATE TO 24 HOUR URINE COLLECTION? Bryan Hinck, Vishnuvardhan Ganesan, Sarah Tarplin, John Asplin, Sri Sivalingam, and Manoj Monga Bryan HinckBryan Hinck More articles by this author , Vishnuvardhan GanesanVishnuvardhan Ganesan More articles by this author , Sarah TarplinSarah Tarplin More articles by this author , John AsplinJohn Asplin More articles by this author , Sri SivalingamSri Sivalingam More articles by this author , and Manoj MongaManoj Monga More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2145AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To determine if there is correlation between night time 12 hour urine super-saturation (SS) of calcium oxalate (CaOx), calcium phosphate (CaP), or uric acid (UA) to traditional 24 hour urine collection. METHODS Following IRB approval and informed consent, patients completed two 24 hour urine collections, with each collection divided into two separate 12 hour collections. Day time collection began after the first morning void and continued for 12 hours, ending with a terminal void. The night collection proceeded for the next 12 hours through the first morning void. Patients collected 2 separate 24 hour collections. Our hypothesis was that the night time SS will correlate with 24 hour SS levels. RESULTS 40 patients completed two 24 hour collections. 28 patients had < 20% variation in creatinine excretion between the 2 days, were deemed to be accurate collections, and were further analyzed. The male to female ratio was 11:17 with a mean age of 58.68 + 11.78 and mean BMI of 30.1 + 7.6. Seven collections had elevated 24 hr SSCaOx levels (> 10.0); in all cases, the night time SSCaOx was also >10.0. 18 collections had elevated 24 hr SSUA levels (> 1.0); in 15 of these cases, the night time SSUA was also > 1.0. Only 4 collections had elevated 24 hr SSCaP (> 1.0); therefore it is difficult to draw any meaningful analysis. Overall, there was strong correlation between night time SS and the 24 hr SS (Figures 1-3) using all 56 collections, with SSUA having the strongest positive correlation (R2=0.7885). Statistical analysis was performed using JMP (SAS, Cary, NC). CONCLUSIONS A 12-hour night-time collection was 100% and 83% sensitive at detecting an elevated SS for CaOx and UA respectively. As such, simplifying the metabolic evaluation to a 12 hour overnight collection may be feasible – improving compliance and decreasing patient burden. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e1073-e1074 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Bryan Hinck More articles by this author Vishnuvardhan Ganesan More articles by this author Sarah Tarplin More articles by this author John Asplin More articles by this author Sri Sivalingam More articles by this author Manoj Monga More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...