MP8-11 IS PREOPERATIVE UTI ASSOCIATED WITH INCREASED RISKS OF UTI AFTER URETEROSCOPIC LITHOTRIPSY ? - A NATIONWIDE POPULATION-BASED STUDY

Abstract

You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Kidney & Bladder1 Apr 2014MP8-11 IS PREOPERATIVE UTI ASSOCIATED WITH INCREASED RISKS OF UTI AFTER URETEROSCOPIC LITHOTRIPSY ? - A NATIONWIDE POPULATION-BASED STUDY Eric Y.H. Huang, Hsiao-Jen Chung, Chih-Chieh Lin, Ruo-Sin Peng, Allen W. Chiu, Alex T.L. Lin, and Kuang-Kuo Chen Eric Y.H. HuangEric Y.H. Huang More articles by this author , Hsiao-Jen ChungHsiao-Jen Chung More articles by this author , Chih-Chieh LinChih-Chieh Lin More articles by this author , Ruo-Sin PengRuo-Sin Peng More articles by this author , Allen W. ChiuAllen W. Chiu More articles by this author , Alex T.L. LinAlex T.L. Lin More articles by this author , and Kuang-Kuo ChenKuang-Kuo Chen More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.354AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Preoperative symptomatic urinary tract infection (UTI) usually defer the definite management for upper urinary tract stone, such as ureteroscopic lithotriopsy (UL). Meanwhile, whether the chances of postoperative symptomatic UTI will be increased is a main concern for such situation. We investigated whether there is an association between preoperative and postoperative UTI for UL by analyzing a nationwide population-based database. METHODS A urology dataset including 3,433,230 individuals was selected from the National Health Insurance Research Database (NHIRD) of Taiwan for the year 2006 to 2010. The claim data was used for the study. Patients with significant UTI was defined as those who has the diagnosis of UTI and been hospitalized for parenteral antibiotics. Two groups of patients with upper urinary tract stone underwent UL were identified. Patients in Group A had significant UTI resulted in hospitalization within 2 months prior to UL. Patients in Group B, accepted the same procedure but without significant UTI, were randomly selected to match Group A by sex and age. The incidence rate of postoperative significant UTI within 2 months after UL were compared between the 2 groups. The effect of percutaneous nephrostomy tube (PCN) insertion was also analyzed. Chi-square test and logistic regression analysis were used for statistics. RESULTS We identified 1169 patients for Group A and 3507 patients for Group B. The mean age was 59.6 years (range 22-93) for Group A and B. Male to female ratio was 44% to 56%. The incidence rate of postoperative symptomatic UTI was 12.23% and 1.82% for Group A and Group B, respectively (p<0.0001). Age is a significant factor for postoperative UTI in both Group A and B (Odds ratio: Group A 1.025, p=0.0002; Group B 1.058, p<0.0001). PCN insertion is a significant factor for postoperative UTI in Group B but not Group A (Odds ratio: Group A 1.249, p=0.259; Group B 3.955, p=0.0002). (Table) CONCLUSIONS We found that preoperative significant UTI and old age are significantly associated with increased risks of significant UTI after UL. PCN insertion is a risk factor for postoperative significant UTI in patients without significant UTI before UL. The incidence of postoperative significant UTI related to PCN insertion With PCN insertion Without PCN insertion p Group A 15.00% 11.44% 0.1225 Group B 8.43% 1.66% <0.0001 © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e78 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Eric Y.H. Huang More articles by this author Hsiao-Jen Chung More articles by this author Chih-Chieh Lin More articles by this author Ruo-Sin Peng More articles by this author Allen W. Chiu More articles by this author Alex T.L. Lin More articles by this author Kuang-Kuo Chen More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...