MP79-14 NOCTURNAL POLYURIA AND NOCTURNAL BLOOD PRESSURE PATTERNS IN MALE PATIENTS WITH LOWER URINARY TRACT SYMPTOMS

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction II1 Apr 2018MP79-14 NOCTURNAL POLYURIA AND NOCTURNAL BLOOD PRESSURE PATTERNS IN MALE PATIENTS WITH LOWER URINARY TRACT SYMPTOMS Misato Takayama, So Omori, Daiki Ikarashi, Tomohiko Matsuura, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata, Jun Sugimura, Takaya Abe, and Wataru Obara Misato TakayamaMisato Takayama More articles by this author , So OmoriSo Omori More articles by this author , Daiki IkarashiDaiki Ikarashi More articles by this author , Tomohiko MatsuuraTomohiko Matsuura More articles by this author , Yoichiro KatoYoichiro Kato More articles by this author , Mitsugu KanehiraMitsugu Kanehira More articles by this author , Ryo TakataRyo Takata More articles by this author , Jun SugimuraJun Sugimura More articles by this author , Takaya AbeTakaya Abe More articles by this author , and Wataru ObaraWataru Obara More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2682AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Nocturia is the most prevalent symptom of lower urinary tract symptoms (LUTS). The causes of nocturia include bladder storage disorders, nocturnal polyuria, and sleep disorders. Nocturnal polyuria is the largest contributor among these factors. We investigate the prevalence of nocturnal polyuria, their underlying factors, and the patterns of blood pressure variation in patients undergoing treatment for LUTS. METHODS This study was conducted from April 2015 to July 2017.Voided volume, voiding frequency and nocturnal polyuria index were determined using voiding diaries of 242 male patients (65–92years old) undergoing treatment for LUTS, whereas underlying factors were assessed using medical histories and medications. Among 242 patients, 34 (17 each in the nocturnal and non-nocturnal polyuria groups) underwent 24h ambulatory blood pressure monitoring. Measurements and assessments were performed using the portable automatic blood pressure monitor TM-2433 (A&D Company Ltd.) according to the guidelines for the clinical use of 24h ABPM (JCS 2010). Patients whose mean nocturnal blood pressure was lower than diurnal blood pressure by ≥10% and <10% were categorized as dippers, and non-dippers. Moreover, patients whose mean nocturnal blood pressure was higher than their mean diurnal blood pressure were categorized as risers. RESULTS Nocturia and nocturnal polyuria were observed in 194 (81%) and 136 (56.2%) patients, respectively.Among patients with nocturia, 130 patients (67.0%) had nocturnal polyuria, the rate of which increased with increased nocturnal voiding frequency.Significantly higher usage rates of two or more anti-hypertensives (including combinations) were observed in the nocturnal polyuria group than in the non-nocturnal polyuria group (p = 0.0351). Analysis of 24-h blood pressure variation showed that significantly higher non-decreased nocturnal blood pressures (i.e., non-dippers and risers) were observed in the nocturnal polyuria group than in the non-nocturnal polyuria group (p = 0.0365)(Fig1). CONCLUSIONS The nocturnal polyuria group had significantly higher proportions of patients who did not exhibit lowered nocturnal blood pressure, indicating the potential therapeutic value of interventions that lower nocturnal blood pressure to improve nocturnal polyuria. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1086 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Misato Takayama More articles by this author So Omori More articles by this author Daiki Ikarashi More articles by this author Tomohiko Matsuura More articles by this author Yoichiro Kato More articles by this author Mitsugu Kanehira More articles by this author Ryo Takata More articles by this author Jun Sugimura More articles by this author Takaya Abe More articles by this author Wataru Obara More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...