MP79-10 EFFECTS OF TRAINING AND MECHANICAL FORCE OF ULTRASOUND ON BLADDER FILLING: REPEATABILITY OF ORAL HYDRATION STUDIES IN HEALTHY ADULTS

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction II1 Apr 2018MP79-10 EFFECTS OF TRAINING AND MECHANICAL FORCE OF ULTRASOUND ON BLADDER FILLING: REPEATABILITY OF ORAL HYDRATION STUDIES IN HEALTHY ADULTS Derek Sheen, Anna S. Nagle, Hiren Kolli, Naomi N. Vinod, Hameeda A. Naimi, Uzoma A. Anele, Stefan G. De Wachter, John E. Speich, and Adam P. Klausner Derek SheenDerek Sheen More articles by this author , Anna S. NagleAnna S. Nagle More articles by this author , Hiren KolliHiren Kolli More articles by this author , Naomi N. VinodNaomi N. Vinod More articles by this author , Hameeda A. NaimiHameeda A. Naimi More articles by this author , Uzoma A. AneleUzoma A. Anele More articles by this author , Stefan G. De WachterStefan G. De Wachter More articles by this author , John E. SpeichJohn E. Speich More articles by this author , and Adam P. KlausnerAdam P. Klausner More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2678AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Currently, ICS-defined verbal sensory thresholds are the only objective measures of real time bladder sensation in the micturition filling phase. A non-invasive protocol was previously developed using 3D ultrasound and a sensation meter to more completely characterize real time bladder sensation and its correlation with bladder volume/shape/rhythm. This study validates the protocol by measuring the effects of participant training and ultrasound probe pressure in oral hydration studies. METHODS Healthy volunteers with no urinary symptoms (ICIq-OAB scores) were recruited into an oral hydration study. Throughout 2 complete fill/void cycles, the participants drank 2L Gatorade G2 and used a touch-screen sensation meter. Participants used the sensation meter to record real-time bladder sensation (0-100%). The study was repeated 3 times, once a week (Visits A, B, and C). In visits A and B, ultrasound images were obtained every 5min. The ultrasound was not used in visit C. For each 5% sensation increment, bladder volumes were calculated by measuring the bladder capacity/time (assuming constant fill rates). RESULTS 10 participants (3 male/7 female) completed all visits. Fig1 shows %sensation vs. %capacity. In the group receiving ultrasound, the untrained participants (A1) had a decreased sensation (left shift) occurring mainly at low capacities (5-50%), likely representing the effect of training. With the removal of the ultrasound (C1 and C2), there is a further decrease in sensation (left shift), likely representing an additional sensation effect from the ultrasound probe. CONCLUSIONS Because both visits A and B had ultrasound, the decreased sensation (left shift) at low capacities likely represents the effects of training (Fig1, red arrow). In visit C where the ultrasound probe was withheld, there was a further decrease in sensation (left shift), likely due to the probe pressure (Fig 1, blue arrow). This validation study demonstrates that during oral hydration studies, training and ultrasound probe pressure can affect real-time bladder sensation. This will further clarify variables that influence non-invasive metrics for filling phase sensation. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1084 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Derek Sheen More articles by this author Anna S. Nagle More articles by this author Hiren Kolli More articles by this author Naomi N. Vinod More articles by this author Hameeda A. Naimi More articles by this author Uzoma A. Anele More articles by this author Stefan G. De Wachter More articles by this author John E. Speich More articles by this author Adam P. Klausner More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...